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management rheumatology syndrome causes differential lupus nephrology neurology sle systemic workup abscess activation arteritis arthritis cell cerebritis cns crisis disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Disease, PRES Pathophysiology ... permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment:
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Malignancy (e.g ... . hematologic) ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Infection (eg ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Syndrome (SPS) - Diagnosis ... and pernicious anemia ... Person Syndrome Pathophysiology ... Person Syndrome Treatment ... #Management #treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Lung Abscess Pathophysiology ... Leukocytosis, anemia ... hemorrhage • Treatment ... • Vasculitis (e.g
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... E.g. 80 yo ESR cutoff ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Systemic lupus erythematosus ... the presence of anemia ... inflammatory disease (e.g ... Chemistry profile (e.g ... (to support a diagnosis
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... other pathology (e.g ... (short-acting, e.g ... Renal #Crisis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
search for and treatment ... - Cytopenias (anemia ... Pathophysiology ... Treatment Approach ... #Management #Hematology
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