67 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: when any egg ... Neurological Compromise (e.g ... Cardiac Compromise (e.g ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
antagonist use (e.g ... adjunct therapy) e.g ... adjunct therapy) e.g ... #Management #pathophysiology ... #immunology
Pericardial Tamponade
Beck's Triad 
1. Hypotension 
2. Jugular venous distension 
3. Muffled heart sounds 
Patient will be
Jugular venous distension ... paradoxus - ECG ... collapse of RV - Treatment
Summary of Heart Blocks
1st Degree Heart Block:
 • Prolonged PR >200ms (5 small squares).
 • Narrow
• No Treatment ... : Pacemaker 3rd ... : Pacemaker - Will ... summary #Diagnosis #EKG ... electrocardiogram #ecg
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Lipid mediators (e.g ... Other mediators (e.g ... inflammatory mediators (e.g ... #Anaphylaxis #pathophysiology ... #immunology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... #Pharmacology #Pathophysiology ... #immunology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Dysplasias • (e.g ... Panhypopituitarism Treatment ... Disease • GI (e.g ... IBD) • Renal (e.g ... Metabolism Error • Immunologic
A wandering atrial pacemaker, (WAP), is an atrial arrhythmia that occurs when the natural cardiac pacemaker
wandering atrial pacemaker ... identifiable on ECG ... rarely causes symptoms ... or requires treatment ... Clinical #MedStudent #EKG
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
• Indolent symptoms ... , hemoptysis Treatment ... • Carbapenem (e.g
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG