14 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... ) Loop agents (eg ... #Diuretics #Sites ... #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... and Their Site ... 3) Loop Diuretics ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Metabolic Alkalosis: Differential ... Diagnosis ECF ... thiazide-sensitive site ... #Diagnosis #Causes ... #nephrology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
of Polyuria - Differential ... Diagnosis Excess ... a.k.a. osmotic diuresis ... SGLT2 inhibitors (e.g ... #nephrology
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
Polyuria - Differential ... Diagnosis Algorithm ... mosm/kg • Solute Diuresis ... solute intake (e.g ... #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Hypernatremia - Differential ... Diagnosis Algorithm ... administration • Osmotic diuresis ... Polyuria scheme) e.g ... Hypernatremia #Nephrology
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
of Polyuria - Differential ... Diagnosis Algorithm ... /min) Osmotic Diuresis ... concentration (e.g ... #Differential #
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Diagnosis and Treatment ... The differential ... , Dehydration: neurologic ... unavailable 2) Osmotic Diuresis ... patient weight (eg
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... venom from animal bites ... electromyographic (EMG ... #Diagnosis #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... Diagnosis Approach ... classes, including a diuretic ... heart failure, neurologic ... Neurologic disorders