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diagnosis differential reactions allergy comparison hypersensitivity management oncology rheumatology acidosis allergic anemia atlas basics blood bruising cryofibrinogenemia cryoglobulinemia cryoglobulins definitions
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80-100 fL) • Bleeding ... Chronic Disease (e.g ... #Anemia #MCV #Classification ... #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Rare • Drugs (e.g ... Coagulation #Bleeding ... #Causes #Hematology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... cell antigens, leading ... Antigen-antibody complex ... Antigen-antibody complexes ... allergy #table #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... #classification
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types ... : Classification ... on: - Cell type ... Hepatosplenomegaly, cytopenias(bleeding ... #differential #hematology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... for ~3/4 of cases ... (uncommon) • Bleeding ... VonWillebrand #Disease #Classification ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... Paradoxical spontaneous bleeding ... Divided Into Two Types ... cryoglobulins • Negative causes ... #hematology
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... antigen-surface complex ... antibody-antigen complexes ... exposure to allergen causes ... #Classification
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... normal in mild cases ... Establish hemophilia type ... (e.g. ... Management #treatment #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... the patient’s complete ... #typea #typeb # ... classification
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