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Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Normal PTH: • Hyperparathyroidism ... : Parathyroid adenoma ... , Parathyroid carcinoma ... Diagnosis #Algorithm #Workup
Hypocalcemia Laboratory Evaluation Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
hypocalcemia: - Hypoparathyroidism ... activating mutation - Parathyroid ... Laboratory #Levels #Hyperparathyroidism
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 Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Hypercalcemia Parathyroid ... structure-related • Primary hyperparathyroidism ... • Parathyroid ... adenoma • Parathyroid ... disease • Tertiary hyperparathyroidism
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Hypercalcemia Parathyroid ... hormone–dependent Primary hyperparathyroidism ... type 2A, familial hyperparathyroidism ... ) Parathyroid hormone–independent ... Neoplasms - Parathyroid
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 Radial Fracture Due to Parathyroid Carcinoma- ...A plain radiograph of the left arm showed a diaphyseal
Fracture Due to Parathyroid ... diagnosis of primary hyperparathyroidism ... with an intact parathyroid ... cause of primary hyperparathyroidism ... radial #fracture #hyperparathyroidism
Hypocalcemia - Differential Diagnosis Algorithm • Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced
Elevated - Secondary Hyperparathyroidism ... Inappropriately Normal/Low - Hypoparathyroidism ... Destruction of parathyroid
Hypomagnesemia (Serum level < 1.7 mg/dL) Neuromuscular manifestations • Tremor, tetany, seizures • Weakness
Hypocalcemia • Hypoparathyroidism ... • Parathyroid
Hypocalcemia Workup - Differential Diagnosis Algorithm • Low Magnesium, High Magnesium - Functional Hypoparathyroidism • High
Hypocalcemia Workup ... Magnesium - Functional Hypoparathyroidism ... Phosphate, Low PTH - Hypoparathyroidism ... #Hypocalcemia #Workup
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate LOW PHOSPHATE - Low/NormaI PTH
NormaI PTH • Hypoparathyroidism ... Resistance (Pseudo-hypoparathyroidism ... Low PTH • Hypoparathyroidism ... • Secondary Hyperparathyroidism
Hypercalcemia Evaluation Algorithm (PTH = parathyroid hormone; PTHrp: parathyroid hormone–related peptide.) #Hypercalcemia #Evaluation #Algorithm #Diagnosis
Algorithm (PTH = parathyroid ... hormone; PTHrp: parathyroid
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