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differential management oncology syndrome classification essential et leukemia lymphadenopathy lymphomas lymphoproliferative lysis nonhodgkin pathophysiology sapho thrombocythemia thrombocytosis tls tumor
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Infectious: • Acute ... • Rheumatic disorders ... effect following treatment ... #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Fatigue • Acute ... Lymphadenopathy #LAD ... #Algorithm #Causes ... #Hematology #Oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... high WBC count cause ... - ACS, AKI, acute ... Syndrome #TLS #diagnosis ... #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... lymphadenopathy more diffuse ... Treated Like Acute ... pathophysiology #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... ↑ Can develop leukostasis ... #Leukemia #Hematology ... #Oncology #Diagnosis
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
atypical chest pain ... hemoproliferative disorder ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #hematology
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