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diagnosis differential management oncology blood lymphadenopathy product reactions syndrome diffuse disorders eosinophil essential et focal leukemia leukostasis localized lysis sapho
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... for secondary causes ... (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - DRESS - AIN ... Mastocytosis - Acute ... Differential #Diagnosis #Causes ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Infectious: • Acute ... effect following treatment ... #Causes #Hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Differential Diagnosis Algorithm ... Epitrochlear (Always pathologic ... Lymphadenopathy #LAD ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Fatigue • Acute ... Lymphadenopathy #LAD ... #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... activity • ↓ LAP ... -> AML: Blast crises ... • (Peripheral eosinophilia ... #Leukemia #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... TNF blockers had ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... : Fever, flank pain ... Causes purpura & ... Transfusion Related Acute ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... : Fever, flank pain ... Causes purpura & ... Transfusion Related Acute ... diagnosis #management #hematology
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