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differential management table antibody nuclear vasculitis antibodies arteritis arthritis autoimmune challenges classification criticalcare cryofibrinogenemia cytoplasmic disorders fluid gca giantcell infections
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... phenomenon, SjS, cancer ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... phenomenon, SjS, cancer ... #Testing #Nuclear ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... : The ANA patterns ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Associated Features: Cancer-associated ... heliotrope, shawl sign ... : Proximal and distal ... #differential #diagnosis ... #comparison #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
for 21% of all cancers ... Conditioning regimen Signs ... , unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Pulmonary Embolism ... life-threatening causes ... #Signs #Presentation ... #comparison #Table ... #Diagnosis
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 TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
• Is there a pattern ... noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused ... #MSK #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... thrombophlebitis, pulmonary ... Biopsy: Typical pathologic ... #rheumatology # ... hematology
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