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rheumatology management differential table dermatomyositis rash vasculitis acrodermatitis allergy anaphylaxis antimda5 antimda5dm antinxp2 antinxp2dm arteritis atrophicans autoimmune behcet biliary cholangitis
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous manifestations ... chest (in a V-sign ... auricular papules Clinical ... anti-NXP2 Abs Lung Manifestations ... #dermatology #diagnosis
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Body System Dermatologic ... tongue and lips - Skin ... abdominal cramps Neurologic ... #Allergy #Signs ... #Symptoms #Anaphylaxis
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 Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 100,000, Typically Age ... druginduced #lupus #sle #comparison ... #diagnosis #management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Manifestations ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
European descent • Age ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Examination: • Skin
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to 40 years of age ... Manifestations: ... injury) • Neurologic ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Manifestations depend ... Diagnosis = clinical ... required due to skip ... #Symptoms #Diagnosis
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... Underlying valve pathology ... in up to 30% of cases ... #Endocarditis #comparison
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... Risk factors: Age ... Transfusion #Reactions #hematology ... #diagnosis #comparison
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