12 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyarteritis nodosa • Microscopic ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rheumatology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Nephrotic syndrome ... Anti-GBM disease • Granulomatosis ... diseases #nephrology #pathology ... #comparison #table ... #diagnosis #microscopy
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... - Wegener granulomatosis ... - microscopic ... #Rheumatology # ... Diagnosis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Urticarial/LCV) - Cryoglobulinemic ... Associated: - Microscopic ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... vasculitis - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis ... #types #classification ... #rheumatology #
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... Wegener's granulomatosis ... Microscopic polyangiitis ... Associations #diseases #diagnosis ... #table #rheumatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Diagnosis ... Biopsy: Typical pathologic ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... ANCA +MPO) • Cryoglobulinemic ... Dx: GPA, EGPA, microscopic ... #rheumatology # ... classification