9 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... Microscopic polyangiitis ... - MPO>PR3 - ANCA ... #ANCA #Antineutrophil ... #rheumatology #
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
- C-ANCA pattern ... P-ANCA pattern ( ... >MPO Microscopic ... Anti-GBM disease ... #Rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
ANA - Non-specific ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... Microscopic polyangiitis ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... : The ANA patterns ... Rheumatic Diseases ... • Rheumatic Diseases ... #patterns #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
-ANCA): • Microscopic ... Vasculitis: + MPO-ANCA ... diseases, such ... Dx: GPA, EGPA, microscopic ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: ANCA Associated ... Pauci Immune (ANCA ... -ANCA)): Microscopic ... No Granulomas (ANCA ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
: • ANCA-associated ... vasculitis, rheumatoid ... Serositis Labs: • ANA ... antibodies • (-) ANA ... #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... classification #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... antibody (ANA) ... ACE level, CXR, ANCA ... #Disease #Rheumatoid