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diagnosis causes injury ascites aflp albumin chemistry druginduced elevated fatty function gradient hepatocellular hypertension interpretation liverenzymes management obgyn obstetrics pathophysiology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Chronic Viral Hepatitis ... Viral Hepatitis ... (>1000): • DILI ... Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 20x normal - Acute ... Viral Hepatitis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... • Autoimmune hepatitis ... • Iatrogenic: DILI ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... • Infections: Hepatitis ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... dechallenge • Acute ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... • Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... Sepsis, Viral Hepatitis ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #injury #hepatitis ... #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
- Alcoholic hepatitis ... fibrosis - Acute ... fatty liver of ... Causes #diagnosis #differential ... #hepatology #SAAG
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
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