45 results
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... Aggressive disease ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... extramedullary disease ... Phosphorus CLL ... -> Invade Skin: ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Chronic Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... Algorithm #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... • Lymphoma • Leukemia ... Myeloproliferative disorders ... • Sickle Cell ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... cells can indicate disease ... lymphoproliferative disorders ... workup #oncology #hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Myeloproliferative Disorders ... Colitis and Crohn’s Disease ... #Basophilia #Differential ... Diagnosis #causes #hematology
A summary of GI Lymphomas - Primary Lymphoid Neoplasms of the GI Tract
T-Cell
 - EATL
 -
the GI Tract T-Cell ... lymphoproliferative disorder ... Lymphomas #GITract #hematology ... #hemepath #pathology ... #differential #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Chronic inflammatory disorders ... Chronic myeloid leukemia ... (CML) - Dr. ... Diagnosis #Causes #hematology