19 results
A summary of GI Lymphomas - Primary Lymphoid Neoplasms of the GI Tract
T-Cell
 - EATL
 -
lymphoproliferative disorder ... #GITract #hematology ... #hemepath #pathology ... #differential # ... diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... e.g. lupus, CLL, lymphoma ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... with or without platelet ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #Anemia #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... #Platelet #Disorders
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... , Auer rod • Lymphoid ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Count - Differential ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... Metastatic cancer, Lymphoma
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... IgM associated lymphoma ... disease, Malignant lymphoma ... RBC #Morphology #differential ... #diagnosis #hematology