11 results
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
#Dysmorphic #RBCs ... #ElectronMicroscopy ... SEM #clinical #pathology ... #hematology #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... Differentiation #Syndrome ... #management #hematology
This image shows acellular scanning EM with a fibrocellular crescent with entrapped RBCs. The glomerulus is
with entrapped RBCs ... fibrocellular #crescent #RBCs ... #ElectronMicroscopy ... SEM #clinical #nephrology ... #pathology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... hyperviscosity syndrome ... : • Pathophysiology ... diagnosis #management #hematology
hematopoiesis - leukocyte maturation tree

- Amy Chung, MD, MSc @AmyChung 

#hematopoiesis #leukocytes #maturation #tree #pathophysiology #Hematology
maturation #tree #pathophysiology ... #Hematology #Progenitor ... #Cells #WBC #pathology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... Miller Fisher Syndrome ... - NORMAL CSF WBC ... management #treatment #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... workup #oncology #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... is similar to PML ... etiologies and PML ... The clinical syndrome ... dementia #AIDS #Neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
anemia (MAHA) Pathophysiology ... rule out other pathology ... Renal #Crisis #rheumatology ... #nephrology #diagnosis