21 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
on SmearChronic ... Decreased RBC ... Thalassemia • RBC ... Disorder • RBC ... #Causes #Hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... anorexia, ARDS ​• RBC ... phase: Peripheral smear ... TREATMENT: ​• Acute ... #diagnosis #management
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... effect following treatment
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... Initial labs: CBC ... Reticulocytes, smear ... #Algorithm #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... C3d • Blood smear ... Anemia #diagnosis #management ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Triggers: Diuretics, PRBC ... - 80% have fever ... • Lab values: WBC ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... Vmphocytosis on routine CBC ... ) B symptoms → fevers ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... • Monitor: CBC ... #Diagnosis #Management ... #Treatment #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if high risk if WBC ... Subacute-Acute: • Common: fever ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Peripheral Blood Smear ... Hgb 12.5, WBC 14 ... Treatment is tetracycline ... initiation of treatment ... BloodSmear #microscopy #pathology