13 results
diagnosis anemia hemolytic oncology rheumatology agglutinin anemias antibody apml arthritis bacilliformis bartonella causes chronic cll cold differentiation disease erythematosus hemeonc
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Decreased RBC ... Thalassemia • RBC ... Disorder • RBC ... #Approach #Differential ... #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... Algorithm Suspected ... Initial labs: CBC ... Reticulocytes, smear ... #Algorithm #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... C3d • Blood smear ... : Differential → ... Anemia #diagnosis #management ... #treatment #rheumatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
hypertension • Unusual RBC ... bartonella (oroya fever ... acanthocytes - Consider RBC ... elliptocytosis, autoimmune ... #workup #hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... anorexia, ARDS ​• RBC ... phase: Peripheral smear ... TREATMENT: ​• Acute ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... Vmphocytosis on routine CBC ... ) B symptoms → fevers ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
if high risk if WBC ... initiation • Differential ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
IgM) • Blood smear ... - RBC agglutination ... younger pts) Differential ... Symptoms: High fevers ... hemolytic #anemia #hematology
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