34 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Potassium Excretion ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... #Renal
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... gastrointestinal K loss • Renal ... hypokalemia • Renal ... #nephrology #potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... loss (Diarrhea) Renal ... Diagnosis #Algorithm #causes ... #potassium #low ... #nephrology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... (steatorrhea) Renal ... osmotic diuresis - Potassium ... Tubulointerstitial renal ... medications #drugs #pharmacology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal ... causes • Laxative ... #nephrology #low
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... deficiency • Renal ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Dermatomyositis) AKI - Pathophysiology ... HYPOTENSION -> renal ... renal ischemia ... Monitor potassium ... Management #Summary #causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
oxoproline) • Renal ... Renal acidosis ... hyperkalemia (with renal ... Potassium-sparing ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... deficiency • Renal ... differential #diagnosis #causes ... #potassium #high ... #nephrology