11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Antimicrobial treatment ... Demyelinating disease ... caused by the JC ... differential #diagnosis #AIDS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... Treatment: • HAART ... disorder #dementia #AIDS ... #Neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... Treat primary cause ... #hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
caused by the protozoan ... symptoms, positive serology ... only available at CDC ... q12h)x60 days • Pediatric ... 90-120 days • Pediatric
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... worsening of that disease ... be present: • AIDS ... pleural effusions, CNS ... pericarditis, peritoneal disease
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... the underlying cause ... • Treatment of
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... MCTD - Bechet disease ... Transverse Myelitis Treatment ... diagnosis #management #neurology