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diagnosis hematology syndromes treatment acromegaly apml chronic classification differentiation encephalopathy fever hemeonc hemophagocytic hlh hodgkins leukemia lymphocytic lymphohistiocytosis lymphoma mds
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Parvovirus infection ... Workup: • Complete ... blood count with differential ... diagnosis #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
pancreatic islet cell ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... Diagnosis and Workup ... #Endocrinology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Preeclampsia, Eclampsia, Infection ... Etiology: • Pathophysiology ... Reversible course Differential ... Diagnosis: • Infection ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... w differential ... confirm DAH, r/o infection ... #differential # ... diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Triggers: ▪ Infections ... Pathophysiology ... of NK cells and CD8 ... underlying trigger: Infections
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... during some or all ... DIFFERENTIAL DIAGNOSIS ... upper respiratory infection ... Serial CBC counts
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