36 results
Initiation of ART in HIV patients with Opportunistic Infections
 • Pulmonary TB and CD4 cell count
Infections • Pulmonary ... TB and CD4 cell ... count <50 • Pulmonary ... of starting OI treatment ... Infections #management #infectiousdiseases
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... : • Pauci-Immune ... Cryoglobulinemia) • Immune ... Investigations • Labs: CBC
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
cell-mediated immune ... antigen-specific CD4 ... culture, PCR, K39) Treatment ... #infectiousdiseases ... #microbiology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology # ... infectiousdiseases
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Inflammatory Syndrome ... (IRIS) - Pathophysiology ... factors: - Low CD4 ... duration or OI treatment ... #Inflammatory #Syndrome
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... despite appropriate treatment ... Treatment Guideline ... diagnosis #management #treatment ... #infectiousdiseases
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... Guillain-Barré syndrome ... antisynthetase syndrome ... , immune-mediated ... Statin Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Inflammatory Syndrome ... Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... #Inflammatory #Syndrome
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Others: Cellular immune ... Unknown cause Treatment
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
• Obstructive: Pulmonary ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... 3) UOP > 0.5 cc ... criticalcare #algorithm #treatment