12 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... : • Immune response ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... • Immune response ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... myopathy, Guillain-Barré ... resolve after DC ... resolve after DC ... Statin Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Others: Cellular immune ... Unknown cause Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... reconstituted immune ... CMV - Retinitis, immune ... albicans • Epstein Barr ... #IRIS #Immune
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Immune Reconstitution ... Syndrome (IRIS) - Pathophysiology ... factors: - Low CD4 ... duration or OI treatment ... Syndrome #IRIS #Pathophysiology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
occur when the CD4 ... Antimicrobial treatment ... required until immune ... recovery (CD4-cell ... InfectiousDiseases #Neurology
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
urinary catheter and immune ... Pathophysiology: ... data • Early treatment ... pyelonephritis CMC
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
cord • Guillain-Barre ... Laboratory studies: • CBC ... axial T1 and T2 Treatment ... diagnosis #causes #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... HIV and with low CD4 ... Treatment: • HAART ... treatment • Cognitive ... dementia #AIDS #Neurology