46 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Findings: • ↑AST/ALT ... Monitor and Treat Complications ... #Pregnancy #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... estrogen such as ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #hepatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
• Myopathy (Also ... caused by hydroxychloroquine ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... or higher • Liver ... diagnosis #workup #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
also be considered ... out additional causes ... If other causes ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... #diagnosis #management ... #hematology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... / Symptoms / Complications ... • As soon as ... Syndrome #MSK #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Syndrome, Ischemic Liver ... cases of arterial ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... occur in utero as ... • This is also ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Blood saves lives ... unnecessary and cause ... ALI is the deadliest ... complication of ... Transfusion #Thresholds #Hematology