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diagnosis hepatology management algorithm oncology gastroenterology lfts hepatitis transaminitis alkaline causes classification enzymes hepatocellular hodgkins lymphoma lymphoproliferative phosphatase workup abnormal
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Liver injury ... hepatocellular injury ... • Acute muscle injury ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... Injury? ... Transaminitis #diagnosis #differential ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Injury: • Hepatic ... #differential # ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Pregnancy #hepatology ... diagnosis #management #pathophysiology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Most common symptoms ... disease - Bone symptoms
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... not required in all ... #Differential #
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... ongoing ↑ LFTs or symptoms ... #differential # ... gastroenterology #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Non-hemolytic Disorders ... of hemolysis or liver ... injury ... examination; nonspecific symptoms ... Congenital #bilirubin #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
suspected HH based on symptoms ... Step 3: All patients ... and hematologic ... disorders. ... ALT, alanine aminotransferase
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