9 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... Dermatomyositis ... rash, Shaw sign, holster ... #rheumatology
Holster Sign in Dermatomyositis

Interestingly, poikiloderma and violaceous erythema can occur in sun protected areas as well
Dermatomyositis ... #Sign #Thighs #SkinRash ... #Dermatomyositis ... #Dermatology #Clinical ... #Photo
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... , Polymyositis/Dermatomyositis ... ANA #patterns #rheumatology ... #diagnosis #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... Intermediate - Faster ... Classification #pathophysiology ... #Hematology #Diagnosis
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Diagnosis? ... eosinophilia and systemic symptoms ... infections, foods, autoimmune ... Vasculitis #LCV #Hand #skinrash ... #photo
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Still disease, dermatomyositis ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Induced Lupus: • Symptoms
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential Diagnosis ... myopathies Diagnostic ... Myositis #Myopathy #rheumatology ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Malignancies ▪ Autoimmune ... Common Signs and Symptoms ... Pathophysiology ... Infections, malignancy, autoimmune ... #Management #Hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
mesothelioma, etc - Autoimmune ... cell lymphoma Pathophysiology ... and the systemic symptoms ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis