12 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #joint #pain #skin
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs #symptoms
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... Heberden's nodes (DIP joints ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... : • Behçet Syndrome ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... , and SLE) • Urinalysis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... and pain of the joints ... symptoms by days ... , breast CA - Hematologic ... Leukocytoclastic vasculitis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... management #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... vesicular eruption • Joints ... • Progressive symptoms ... Palpable purpura, joint
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Arthritis: • Joint ... arthropathy • 90% joints ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Arthritis - Signs and Symptoms ... Complications of DMARDs • Skin ... Vascular: Rheumatoid vasculitis ... Musculoskeletal: Joint ... Thrombocytosis, Felty's syndrome