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diagnosis management algorithm alp phosphatase workup alkphos apml astalt biliary bilirubin causes cell chemistry cholangitis cirrhosis coagulation dic differential differentiation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
disturbance (obstructed liver ... Highest • Bone • Liver ... Most common symptoms ... - Drugs - Primary ... Diagnosis #Algorithm #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Tests - AST, ALT, Alkaline ... CAST) • ALT: primarily ... within liver Alkaline ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... PBC Labs: • Alkaline ... or higher • Liver ... diagnosis #workup #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of urinary ... Hyophosphatasia #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
diagnosis and treatment ... suspected HH based on symptoms ... and hematologic ... ALT, alanine aminotransferase ... diagnosis #management #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... : • Treat primary ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • Primary ... Common Signs and Symptoms ... - Elevated liver ... Pathophysiology ... Diagnosis #Management #Hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
common - GI tract, liver ... except for the primary ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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