16 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... acidosis including ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acidosis ↑ ↑ ... Metabolic acidosis ... D-lactate (short bowel syndrome ... MDaniyalHashmi1 #AcidBase ... Diagnosis #Summary #Nephrology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... Acidosis, Respiratory ... Aspirin #Toxicity #Toxicology ... #Treatment
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Hyperlactatemia • Metabolic ... acidosis • Rhabdomyolysis ... PRIS #Diagnosis #Management ... Pharmacology #Toxicity #Toxicology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... , Heat stroke, Metabolic ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... cerebritis #diagnosis #management ... #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... Heat stroke - Metabolic ... Differential #Diagnosis #Management ... #nephrology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... lidocaine, +/- pre-treatment ... • Increased metabolic ... #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... epilepticus Treatment ... #diagnosis #management ... #neurology