69 results
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Acidosis (HAGMA ... with short bowel syndrome ... Aspirin - salicylate toxicity ... causes lactic & ... #Acidosis #HAGMA
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Low intake • Metabolic ... acidosis: Gl tract ... Renal Losses: • Metabolic ... acidosis: Proximal ... Diagnosis #Algorithm #causes
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... no respiratory cause ... show anion-gap metabolic ... acidosis 4) Presentation ... diagnosis #management #Treatment
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... Amyl nitrite - causes ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... LacticAcidosis #Toxicity
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Metabolic acidosis ... D-lactate (short bowel syndrome ... starvation, diabetic) Causes ... Acetazolamide Causes ... - Salicylates Causes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
diuretic use, Bartter syndrome ... , Gitelman syndrome ... acidosis: Chronic ... acidosis: Diabetic ... Diagnosis #Algorithm #causes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... acidosis due to ... the indicated causes ... acidosis, a high
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
Abdominal pain, nausea ... deterioration Shock and metabolic ... acidosis (12-48 ... - Anion gap metabolic ... acidosis with both
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... • Incr Glucose Metabolism ... - Metabolic ... Acidosis • Shift ... #diagnosis #pathophysiology