30 results
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... of carbohydrate metabolism ... state and fat metabolism ... #Pathophysiology ... DKA #Diabetes #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic Ketoacidosis ... Definition of EuDKA • Metabolic ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
bodies are a normal metabolic ... fatty acid (FA) metabolism ... (pH < 7.35) w/ elevated ... differential #diagnosis #management ... #endocrinology
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
• Serum BHB elevated ... Crisis #Algorithm #management ... #endocrinology ... Diabetes #DM2 #Ketoacidosis
Tetralogy of Fallot Summary
 • Anatomy
 • Incidence
 • Pathophysiology
 • Presentation
 • Common Variants
 •
• Incidence • Pathophysiology ... palliation • Post-Op Management ... Fallot #diagnosis #management ... #cardiology #peds ... #pediatrics #treatment
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... falsely normal/elevated ... Due to neuronal metabolism ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Low calcium • Treatment ... TLS #diagnosis #management
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Diagnosis and Management ... show anion-gap metabolic ... , Tachycardia, Elevated ... Labs: Anion-Gap Metabolic ... #Treatment
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... lidocaine, +/- pre-treatment ... • Increased metabolic ... Hemorrhage #ICH #elevated
PCOS Treatment
1st line = weight loss
 • 5-10% weight loss can restore ovulatory cycles
 • Improvement
PCOS Treatment ... Improvement of metabolic ... waxing #PCOS #Treatment ... #management #endocrinology