18 results
Vitamin D Metabolism

#VitaminD #Metabolism #Pathophysiology #Endocrinology #Pathways
Vitamin D Metabolism ... #VitaminD #Metabolism ... #Pathophysiology ... #Endocrinology
Vitamin D Metabolism Pathways

Dr. Jamie Willows @jamiekwillows

#VitaminD #Metabolism #Pathways #pathophysiology #endocrinology
Vitamin D Metabolism ... jamiekwillows #VitaminD ... #Metabolism #Pathways ... #pathophysiology ... #endocrinology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Vitamin D Metabolism ... Fat-soluble vitamin ... mendesthiagob #VitaminD ... #Metabolism #endocrinology ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... #signs #symptoms ... #endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
PTH, ↑Calcium, ↑Vitamin ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
varied clinical symptoms ... There are several symptoms ... (shown in the video ... #neurology #endocrinology ... #hypothyroid
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... during the initial hyperthyroid ... ‘Leakage’ symptoms ... Hashitoxicosis #Hashimotos #Endocrinology ... #Diagnosis #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Radiation • Metabolic ... /endocrine: Vitamin ... Endocrinopathies: Hypothyroid ... • Metabolic myopathies ... Differential #Diagnosis #neurology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
from hormonal and metabolic ... Hypo-Mg2+ • Vitamin ... overload) Other Symptoms ... • Pellagra • Vitamin ... Differential #Diagnosis #Pathophysiology