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diagnosis hematology management syndrome workup aflp biliary cell cholangitis classification coagulation disseminated emergencies fatty hemeonc hepatopulmonary hepatorenal hodgkins hps hrs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... Pathophysiology ... intralobular bile ducts causes ... diagnosis #workup #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... or venipuncture sites ... : • Treat primary ... cause • Correct ... #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
free fatty acid metabolism ... = nonspecific (nausea ... rapidly develops (DIC ... , ascites, jaundice ... Liver #Pregnancy #hepatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... G6PD first) DIC ... Treat underlying cause ... Lower-extremity weakness, urinary ... sticky” cells; WBC
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... + distinctive primary ... Fibrinolysis & DIC ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... Based on number of sites ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... arteriovenous shunting causes ... • Stigmata of cirrhosis ... : jaundice, ascites ... #diagnosis #hepatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
liver disease: cirrhosis ... Pathophysiology: ... diuretic-resistant ascites ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
appearance Favored Sites ... except for the primary ... • CBC + diff • ... Bone marrow Treatment ... #Plasmacytoma #Oncology
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