23 results
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
#Lactulose #pharmacology ... #mechanism #ammonia ... #hepatology #pathophysiology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... namely, the many causes ... many non-hepatic causes ... and decreased metabolism ... #Pathophysiology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in Cirrhosis ... • Pathophysiology ... #BetaBlockers #Cirrhosis ... #hepatology #management ... #pharmacology #
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Acquired (e.g., iHD) Cirrhosis ... Hyperthyroidism - Increased Metabolism ... #HeartFailure #CHF ... #Pathophysiology ... Diagnosis #cardiology #causes
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Non-cirrhotic Hyperammonemia ... Y t amino acid metabolism ... Starvation (↑ muscle catabolism ... Hyperammonemia #ammonia ... Differential #Diagnosis #Pathophysiology
Tweetorial - What's the deal with Ammonia in hepatic encephalopathy?

Aims
Try to answer this question while also
the deal with Ammonia ... also showing 1) Ammonia ... Encephalopathy #Sarcopenia #Cirrhosis ... #Tweetorial #Hepatology ... #Pathophysiology
Medications Used in Congestive Heart Failure

In CHF, the heart is failing as a pump; cardiac output
Heart Failure In CHF ... insuffcient to meet the metabolic ... CHF also causes ... therapy in chronic CHF ... #Pharmacology #CHF
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
CMV), Alcoholic cirrhosis ... NASH, Genetic / Metabolic ... 1 - Ischemia, CHF ... Liver #Injury #hepatology
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
Plasma-Lyte - Causes ... - Causes lactic ... patients with cirrhosis ... patients with a metabolic ... #Crystalloids #pharmacology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... angioedema) • Metabolism ... amount of hepatic metabolism ... #Indications #Pharmacology ... #hematology