11 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
and Type of Liver ... Injury #Medications ... #Differential #DrugInduced ... #LiverInjury #Hepatology ... #Pharmacology #
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Injury - Pathophysiology ... BrighamChiefs #DILI ... #DrugInduced #Liver ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Diagnosis Algorithm DILI ... duration), Several medications ... #DrugInduced #Liver ... Diagnosis #Algorithm #hepatology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... • Indications: ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology ... #indications #dosing
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology ... Mechanisms #DOAC #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... 10x ULN), ↑Tbili/Dbili ... #Pregnancy #hepatology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... Tranexamic #Acid #Indications ... #Pharmacology # ... hematology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications ... #druginduced
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Homeostasis In the liver ... step in purine metabolism ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... and decreased metabolism ... ileal conduit - Medications ... deficiency #Ammonia #Pathophysiology