41 results
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
caused by a toxic ... or metabolic disorder ... Toxic and metabolic ... causes include ... Classification #Diagnosis #Neurology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... show anion-gap metabolic ... Dizziness, Altered, Seizure ... Labs: Anion-Gap Metabolic ... Aspirin #Toxicity #Toxicology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... Neurocysticercosis, PML • Metabolic ... Eclampsia, Prophyria #Seizures ... Diagnosis #Algorithm #Causes ... #neurology
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
rely upon rapid seizure ... The longer the seizure ... epilepticus which may cause ... epilepticus may cause ... #Management #Neurology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Amyl nitrite - causes ... Cyanide #Toxicity #Toxicology ... #Pathophysiology ... #Management #Treatment
Causes of Secondary / Provoked Seizures - Differential Diagnosis Algorithm
Febrile
Infection
 • Sepsis
 • Encephalitis
 • Meningitis
Metabolic
Causes of Secondary ... / Provoked Seizures ... • Meningitis Metabolic ... #Neurology #Differential ... Diagnosis #Algorithm #Causes
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
mentd status, Seizures ... Hyperthermia (most common cause ... SerotoninSyndrome #management ... #toxicology #REBELEM
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... Clozapine is known to cause ... neutropenia - seizures ... #Clozapine #Toxicology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
ICH Management ... Manage ICP and Seizures ... = dilated BV = raises ... • Increased metabolic ... #management