39 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
and Treatment of Metabolic ... Intravenous fluids • Renal ... hydroxide • Hyperkalemia ... treatment • Hypocalcemia ... TLS #diagnosis #management
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Algorithm Extra-renal ... Low intake • Metabolic ... loss (Diarrhea) Renal ... potassium #low #nephrology
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
Treatment of hyperkalemia ... to diuretic #hyperkalemia ... #kaliuresis #management ... #criticalcare # ... diuretics #diuresis #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Metabolic alkalosis ... Renal artery stenosis ... NephTwitter) #Hypokalemia ... Causes #Workup #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Diagnosis Algorithm Hypovolemia ... UNa > 20: • Renal ... tubal acidosis and metabolic ... wasting syndrome Hypovolemia ... Algorithm #Causes #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Non-anion Gap Metabolic ... oxoproline) • Renal ... Renal acidosis ... aniongap #NonGap #Metabolic ... diagnosis #causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... suggests extra-renal ... Pressure: - Metabolic ... Hippurate - Metabolic ... differential #potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
infusions) - Metabolic ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
Checklist Approach to Hypokalemia ... 3.5 - Severe renal ... monitoring depend on renal ... monitoring depend on renal ... #Management #CriticalCare