30 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
particularly underlying renal ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis ... #management #nephrology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
pressure incr renal ... edgarvlermamd - Nephrology ... HepatoRenal #Syndrome #Nephrology ... #Management #Pharmacology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... with a mix of renal ... #Clozapine #Toxicology ... Toxicity #Diagnosis #Pharmacology
Immunosuppression in Transplantation
Induction (I):
 - Basiliximab (Simulect)
 - Alemtuzumab (Campath)
 - Rituximab
 - Anti-Thymocyte Globulin (ATG)
Induction
#Medications #Pharmacology ... #Maintenance #Management ... #Nephrology #Renal
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Excessive vomiting - Metabolic ... - Diarrhea • RENAL ... gas transport, renal ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... , Heat stroke, Metabolic ... Dermatomyositis) AKI - Pathophysiology ... renal ischemia ... Differential #Diagnosis #Management
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
deterioration Shock and metabolic ... - Anion gap metabolic ... coagulopathy, renal ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
step in purine metabolism ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Hyperlactatemia • Metabolic ... Hyperkalemia and renal ... PRIS #Diagnosis #Management ... #Pharmacology # ... Toxicity #Toxicology