135 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Hypokalemia (renal ... potassium wasting ... Sjögren syndrome, Renal ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
algorithm Decreased renal ... potassium excretion ... • Acute renal ... failure • Chronic renal ... Diagnosis #algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... Low intake • Metabolic ... loss (Diarrhea) Renal ... Algorithm #causes #potassium ... #low #nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... Fluids Shift potassium ... (if preserved renal ... #Hyperkalemia #management ... #potassium #nephrology
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... during hypoxic metabolism ... ketoacidosis Renal ... acids in advanced renal ... GOLDMARK #mnemonic #nephrology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Potassium Excretion ... #Hyperkalemia #Pathophysiology ... Pharmacology #Impaired #Potassium ... #Renal
Emergency management of severe hyperkalemia

#hyperkalemia #management #algorithm #nephrology #Potassium #Treatment
Emergency management ... #hyperkalemia #management ... #algorithm #nephrology ... #Potassium #Treatment
Renal osteodystrophy: Pathogenesis and radiological features.

#Renal #Osteodystrophy #Pathophysiology #Nephrology
Renal osteodystrophy ... #Renal #Osteodystrophy ... #Pathophysiology ... #Nephrology
Renal Tubular Disorders

 • Distal Renal Tubular Acidosis (Type 1)
 • Proximal Renal Tubular Acidosis (Type
Renal Tubular Disorders ... • Distal Renal ... ) • Proximal Renal ... Acidosis #Types #pathophysiology ... #nephrology #diagnosis
Hypomagnesemia (Serum level < 1.7 mg/dL)
Neuromuscular manifestations 
 • Tremor, tetany, seizures 
 • Weakness
Hypokalemia • Renal ... potassium wasting ... Abnormalities of calcium metabolism