48 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic ... Toxicology #Diagnosis #Management
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
constellation of metabolic ... intracellular ions and metabolic ... acutekidneyinjury #Pathophysiology ... Presentation #TLS #Workup
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and
and its active metabolite ... #pharmacology #overview ... druginformation #nephrology
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
imbalances or endocrine/metabolic ... #Pathophysiology ... #Nephrology #CKD
Atrial Fibrillation Overview

Symptoms:
Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

1. Why?
Cardiac:
• Valvular heart disease
•
Atrial Fibrillation Overview ... Drugs/toxins • Metabolic ... Fibrillation #Cardiology #Management
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Metabolic alkalosis ... Diagnosis #Causes #Workup ... #Nephrology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... obgyn #diagnosis #management ... #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Excessive vomiting - Metabolic ... increase may cause metabolic ... decrease may cause metabolic ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
APRV - Overview 

Airway pressure release ventilation (APRV) uses prolonged periods of high continuous positive airway
APRV - Overview ... volutrauma, increased work ... MDaniyalHashmi1 #APRV #CriticalCare ... #Ventilation #Management ... AirwayPressureRelease #Overview
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... → Hypokalemia Metabolic ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis