21 results
Mechanisms of Cocaine induced AKI

 • Rhabdomyolysis
 • Vasculitis
 • Infarction
 • Acute interstitial nephritis
 •
Cocaine induced AKI ... • Rhabdomyolysis ... Cocaine #induced #AKI ... #nephrology #pathophysiology
Pathophysiology of AKI in Rhabdomyolysis

Dr. Muner Mohamed @MunerMohamed1

#AKI #Rhabdomyolysis #Pathophysiology #nephrology
Pathophysiology ... of AKI in Rhabdomyolysis ... #Rhabdomyolysis ... #Pathophysiology ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
, Heat stroke, Metabolic ... Dermatomyositis) AKI ... - Pathophysiology ... oxidative iniury Treatment ... Summary #causes #treatment
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Hemolysis • Rhabdomyolysis ... lysis syndrome • Metabolic ... Elimination: • AKI ... blockers - MCW Nephrology
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
Elevated levels ... days; its level elevated ... of developing AKI ... AKI at lower levels ... unpredictable metabolism
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - ... Heat stroke - Metabolic ... declines > ALT) • AKI ... + myoglobin AKI ... #nephrology
Causes of Metabolic Acidosis with Elevated Anion Gap - Differential Diagnosis Algorithm
Elevated Anion Gap > 12
Causes of Metabolic ... Acidosis with Elevated ... Diagnosis Algorithm Elevated ... secretion • AKI ... MetabolicAcidosis #AnionGap #Nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... fever - ACS, AKI ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Low calcium • Treatment
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
• Labs: - Metabolic ... - AKI - Liver ... Collapse: • Pathophysiology ... normal/mildly elevated ... tissue damage (AKI
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Treatment includes ... #Vancomycin #AKI ... #pharmacology #toxicology ... diagnosis #management #nephrology