35 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Low intake • Metabolic ... Renal Losses: • Metabolic ... SAME, Cushing Syndrome ... , Gitelman syndrom ... Diagnosis #Algorithm #causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... , Gitelman Syndrome ... , Liddle syndrome ... aldosteronism #Metabolic ... Algorithm #Nephrology #Causes
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic ... BP = Bartter's Syndrome ... , Gitelman's Syndrome ... ThePeanutKidney #Metabolic ... #Alkalosis #Causes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Metabolic Alkalosis ... Cl- responsive metabolic ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... Diagnosis #Algorithm #causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... Pressure: - Metabolic ... , Gitelman syndrome ... Hippurate - Metabolic
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm
Cardiac:
 • Congenital Heart Disease
 •
Causes of Apparent ... Myocarditis Metabolic ... Inborn Errors of Metabolism ... • Reye's Syndrome ... #Peds #Pediatrics
Blood gas analysis
Metabolic alkalosis
Measured urine CI
< 10 mEq/L
Saline responsive
> 10 mEg/L
Not saline responsive
- Vomiting or NG
gas analysis Metabolic ... suction Endocrine cause ... H+ loss Renal cause ... diuretics - Bartter syndrome ... - Gitelman syndrome
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... and decreased metabolism ... rare): - Reye syndrome ... (Peds) - Primary ... deficiency #Ammonia #Pathophysiology
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... #Pharmacology # ... medications #causes