60 results
diagnosis differential causes algorithm treatment metabolic neurology alkalosis hyperkalemia hypokalemia criticalcare gitelman low kidney pharmacology acidosis barre chloride crrt diuresis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
• Hypokalemia (renal ... potassium wasting ... , Renal tubular ... #diagnosis #nephrology ... #management #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... Low intake • Metabolic ... loss (Diarrhea) Renal ... Algorithm #causes #potassium ... #low #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Chloride depletion syndromes • Gastrointestinal losses -
Causes of Metabolic ... villous adenomas • Renal ... • Severe potassium ... depletion (serum potassium ... <2 mmol/L) #Metabolic
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK Glycols - ethylene and propylene glycol Oxoproline
High Anion Gap Metabolic ... with short bowel syndrome ... ketoacidosis Renal ... acids in advanced renal ... GOLDMARK #mnemonic #nephrology
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Localization of Renal ... Defects Fanconi Syndrome ... tubule Bartter Syndrome ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... suggests extra-renal ... Pressure: - Metabolic ... #differential #potassium ... #nephrology #low
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... iniury, Compartment syndrome ... , Heat stroke, Metabolic ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
minutes) Decrease potassium ... Fluids Shift potassium ... (if preserved renal ... #Hyperkalemia #management ... #potassium #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
• Refeeding syndrome ... Medications Renal ... Losses Non-renal ... Diagnosis #Algorithm #nephrology ... #low #potassium
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #Primary #Metabolic ... Diagnosis #Algorithm #nephrology
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