13 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... of Metabolic Abnormalities ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... constellation of metabolic ... hyperuricemia, #hyperkalemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... : • Pathophysiology ... hydration - Hyperkalemia ... #TLS #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #Pathophysiology ... #nephrology #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Heat stroke - Metabolic ... HIV, Influenza, TSS ... or compartment syndrome ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... , Heat stroke, Metabolic ... HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... Dialysis for severe hyperkalemia
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... • Male sex • Metabolic ... syndrome • Medications ... Gout #Comparison #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... #rheumatology # ... diagnosis #management #treatment
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... lidocaine, +/- pre-treatment ... • Increased metabolic ... Pressure #ICP #Pathophysiology ... #neurology #neurosurgery
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... epilepticus Treatment ... underlying cause • Treatment