36 results
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment ... of Hepatorenal Syndrome ... #HepatoRenal #Syndrome ... #Pharmacology #Medications ... #Treatment
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
step in purine metabolism ... The gout drug pegloticase ... #Homeostasis #Gout ... #Pathophysiology ... #Pharmacology #Medications
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... → Hypokalemia Metabolic ... #Pathophysiology ... #nephrology #diagnosis
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Memory impairment out ... Therefore, Korsakoff Syndrome ... Encephalopathy Treatment ... #neurology #diagnosis
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... waves (Bradycardia out ... hyperkalemia) BRASH Treatment ... • Aggressive treatment ... diagnosis #management #pathophysiology
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
thiazides) - Gout ... - Metabolic syndrome ... failure - Co-medication ... grade 2-3) - Metabolic ... syndrome, Glucose
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
vasoconstriction syndrome ... Toxic: Alcohol, Medication ... Neurocysticercosis, PML • Metabolic ... Algorithm #Causes #neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Neuropathy • Metabolic ... Hypothyroidism • Medication-induced ... Paraprotein-associated (POEMS syndrome ... diagnosis #causes #neurology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
• Male sex • Metabolic ... syndromeMedications ... cortical bone Treatment ... treatment; consider ... diagnosis #management #treatment
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... Conditions for Gout ... • Male sex • Metabolic ... syndromeMedications