16 results
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Renal failure • Metabolic ... acidosis • ARDS ... Colchicine #Toxicity #Toxicology ... #Symptoms #Signs
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... - Metabolism - ... patients with dementia-related ... #Clozapine #Toxicology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV dementia ... Pathophysiology ... Treatment: • HAART ... treatment • Cognitive ... #AIDS #Neurology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Excessive vomiting - Metabolic ... - Gitelman SIGNS ... increase may cause metabolic ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... lidocaine, +/- pre-treatment ... • Increased metabolic ... Pressure #ICP #Pathophysiology ... #neurology #neurosurgery
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... epilepticus Treatment ... underlying cause • Treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Differential Diagnosis: New-Onset Seizure in the Elderly

STRUCTURAL:
 • Stroke/TIA, Subdural hematoma, mass
 • Traumatic Brain Injury
METABOLIC - Electrolyte ... seizure threshold TOXICOLOGIC ... with all types of dementias ... • Dementia-related ... Seizure #Elderly #Neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... EMG: LMN Signs in ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... dissipation of metabolic ... hyperthermia crisis (late sign ... Phaeochromocytoma Neurologic