11 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... also includes symptoms ... of metabolic acidosis ... LacticAcidosis #Toxicity
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... show anion-gap metabolic ... ingestion/exposure Symptoms ... Labs: Anion-Gap Metabolic ... diagnosis #management #Treatment
The Gastroenterology Consult Primer
Guide to Calling a GI Consult
HPI:
 - Start with reason for consult
The Gastroenterology ... I-liner summary - Symptoms ... : Cardiac/pulm/oncologic ... last meal - Treatment ... Calling #Referral #Gastroenterology
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Checkpoint Inhibitor Toxicity ... Incidence, Symptoms ... Complications and Treatment ... CheckpointInhibitor #Toxicity ... #Pharmacology #Oncology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... effect on negative symptoms ... following first-pass metabolism ... - Metabolism - ... #Toxicology #Toxicity
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... Renal Failure Treatment ... management #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Medication/Drug toxicity ... , Metabolic disturbance ... epilepticus Treatment
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
from hormonal and metabolic ... overload) Other Symptoms ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Functional GI Disorders in IBD - IBD Algorithm

Background:
 • 25-40% of IBD in remission have IBS
remission have IBS symptoms ... correlation of lBS-type symptoms ... narcotic use FGID Pathphysiology ... IBD #Algorithm #gastroenterology ... #management #treatment
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
abatacept for the treatment ... MANAGEMENT: G1 toxicity ... 4-6 weeks G4 toxicity ... Cardiotoxicity #cardiology #oncology ... #management #treatment