20 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... in the distal tubule ... delivery to distal nephron ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Sodium loss from tubules ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology ... #hyponatremia #comparison
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Injury (AKI) - Differential ... Diagnosis Framework ... blood volume • Hypovolemia ... the glomeruli, tubules ... #Diagnosis #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... Diagnosis Algorithm ... • Renal tubular ... #differential # ... #causes #nephrology
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
- Differential ... Diagnosis Algorithm ... Urine pH > 6.0 - Hypokalemic ... #Diagnosis #Algorithm ... #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... EABV) - Consider: Hypovolemia ... Helbert Rondon, MD @NephroMD ... #differential # ... algorithm #causes #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Injury (AKI) - Differential ... Diagnosis Framework ... PRE-Renal AKI: • Hypovolemia ... , Anti-GBM • Tubular ... #Diagnosis #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... tobacco, Renal tubular ... #Causes #differential ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... formation: Renal tubular ... #Diagnosis #Management ... #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Generalized distal nephron ... Metabolic #Acidosis #differential ... #diagnosis #causes ... #nephrology