12 results
Nephron Pathophysiology Study Guide 

- Proximal Tubule
- Loop of Henle
- Distal Tubule
- Collecting Duct

The Kidney Zone

#Nephron
Nephron Pathophysiology ... - Proximal Tubule ... Collecting Duct The Kidney ... Zone #Nephron ... #Nephrology #Pathophysiology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
(AKI) - Differential ... blood volume • Hypovolemia ... the glomeruli, tubules ... • ATN (Acute tubular ... #Diagnosis #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... in the distal tubule ... delivery to distal nephron ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... PRE-Renal AKI: • Hypovolemia ... , Anti-GBM • Tubular ... #Diagnosis #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
causes of Acute Kidney ... Injury AKI - Differential ... , Lupus Acute Tubular ... Abhilash Koratala @NephroP ... #Diagnosis #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Generalized distal nephron ... Chronic progressive kidney ... Metabolic #Acidosis #differential ... diagnosis #causes #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... formation: Renal tubular ... nephrotoxicity to kidney ... tubular cells ... #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... malignancies Treatment ... syndrome • Proximal tubular ... Cancer #Oncology #Differential ... Classification #Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... tobacco, Renal tubular ... #Causes #differential ... #diagnosis #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... Syndrome #diagnosis #nephrology ... #management #pathophysiology