11 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
: Proximal tubule ... : Collecting tubule ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... in the distal tubule ... delivery to distal nephron ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... in cardiorenal syndrome ... damage • Tubular ... #Mechanisms #pathophysiology ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... - Differential ... • Renal tubular ... #differential # ... algorithm #causes #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... tobacco, Renal tubular ... use), Gitelman's syndrome ... #Causes #differential ... #diagnosis #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
ratio 0.5%) Differential ... , Renal tubular ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... formation: Renal tubular ... nephrotoxicity to kidney tubular ... Rhabdomyolysis #Differential ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... iniury, Compartment syndrome ... Dermatomyositis) AKI - Pathophysiology ... formation: Renal tubular ... Dialysis for severe hyperkalemia
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI - Differential ... inhibitors, hepatorenal syndrome ... , Lupus Acute Tubular ... Abhilash Koratala @NephroP ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Capillary leak syndrome ... • Proximal tubular ... Cancer #Oncology #Differential ... Classification #Nephrology