127 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
100% Hepatic, 0% Renal ... 75% Hepatic, 25% Renal ... 20% Hepatic, 80% Renal ... #DOAC #NOAC #Metabolism ... #Pharmacology #
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduced DOAC Dosing ... Fibrillation #DOAC ... Anticoagulation #Pharmacology ... #AFib #Renal #CKD
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Prophylaxis, VTE and Renal ... Dosing Renal ... Apixaban (25% renal ... Anticoagulation #Hematology #Pharmacology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... Rivaroxaban • Renal ... DeLoughery @Bloodman #DOAC ... #dosing #ckd #pharmacology
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... from warfarin to DOACs ... patients with good renal ... Anticoagulation #Pharmacology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Monitoring - Renal ... Anticoagulant #DOAC ... Management #Table #Pharmacology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... #Mechanisms #DOAC
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Renal Effect of ... Synthesis - Renal ... disease -> Decreased renal ... Prostaglandins #Pharmacology ... #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium #Renal
Renal Tubular Disorders

 • Distal Renal Tubular Acidosis (Type 1)
 • Proximal Renal Tubular Acidosis (Type
Renal Tubular Disorders ... • Distal Renal ... ) • Proximal Renal ... • Hyperkalemic Renal ... Acidosis #Types #pathophysiology